Cleanroom Specifications & Classifications

What exactly is cleanroom classification? ISO 14644-1 and older standard FS 209E determine class by the concentration levels of particles. The particles range in size from .1 -.5 microns (µm). The class defines a minimum cleanliness level, not a specific design. However class will greatly impact design considerations such as filtration, HVAC requirements and other design elements. Please call AdvanceTEC to discuss your specific requirements.

U.S. Federal Standard 209E Cleanroom Standards*

Maximum Particles / ft³

ISO

≥0.1 µm

≥0.2 µm

≥0.3 µm

≥0.5 µm

≥5 µm

Class

ISO 3

Class 1

ISO 4

350

Class 10

ISO 5

750

300

100

Class 100

ISO 6

1,000

Class 1,000

ISO 7

10,000

Class 10,000

ISO 8

100,000

700

Class 100,000

Biosafety Levels

Biosafety levels define the levels of containment required for handling various types of biological hazards. In the United States, there are four levels of containment as specified by the Centers for Disease Control and Prevention (CDC). The table below is based on information provided by in CDC publications.

Biosafety Level 1 (BSL-1)

Basic level of protection, appropriate for agents that are not known to cause disease in normal, healthy humans.

Biosafety Level 2 (BSL-2)

Level of protection appropriate for handling moderate-risk agents that cause human disease of varying severity by ingestion or through percutaneous or mucous membrane exposure.

Biosafety Level 3 (BSL-3)

Level of protection appropriate for agents of indigenous of exotic origin with a known potential for aerosol transmission that may cause serious and potentially lethal infections after inhalation.

Biosafety Level 4 (BSL-4)

Highest level of protection, appropriate for exotic agents that pose a high individual risk of life-threatening disease by infectious aerosols and for which no treatment is available.

markets & applications

Technology is advancing at eye popping speeds – cloud computing, artificial intelligence, robotics, autonomous cars – all demanding smarter, faster, more efficient and more reliable devices.

Cleanroom Markets & Applications

Biotech & Pharmaceutical Cleanrooms

Nanotech & Semiconductor Cleanrooms

Cleantech & Renewable Energy

University Cleanrooms

Government Cleanrooms