• Cleanroom Design and Construction
Cleanroom Design and Construction


Cleanroom Resource Library

Project Planning Resources

AdvanceTEC knows that a successful project starts with planning and documenting requirements upfront. Together with an experienced team, proper planning will ensure that your project stays on track from kick-off to commissioning. AdvanceTEC can provide the right level of support, whether you have significant cleanroom expertise or if this is your first project. Provided below is some information to help you get started.

Initial Considerations

The decision has been made. You need a cleanroom for your company, university, or research lab – and now it’s up to you to get the project started. The information below serves as a useful checklist to identify some of the initial items you need to know to help you budget, plan and ultimately complete the cleanroom project you envision.

Budgeting Phase

  • What is the size cleanroom, including both square footage and interior ceiling heights?
  • What are the cleanliness classes of the various areas of the cleanroom?
  • What type of application will the cleanroom will be used for (nanotech, semiconductor, biotech, pharmaceutical, others)?
  • Are there specific requirements for sound, light levels, vibration, explosion proof, trace metals, bio hazards or other specialized requirements?
  • What process, production or analytical equipment or tools will be housed inside the cleanroom?
  • What are the process utilities needed for the equipment and tools, such as gases, electrical, exhaust and drains?
  • What is the total exhaust load for the cleanroom?
  • What is the total heat load of the equipment running in the cleanroom?
  • What are the architectural finishes required?
  • What is driving the selection of architectural finishes, such as cGMP compliance, environmental performance, aesthetics or matching an existing area?

Important budgeting note: While cleanroom architectural finishes are not inexpensive, it is AdvanceTEC’s experience that the HVAC Mechanical, Electrical and Plumbing (including high purity lines, waste abatement, etc.) comprises the a greater part of every cleanroom budget – not the walls, floors, doors or ceiling systems.

Planning Phase

  • What is the required date that you need to be ready to start to move in the first pieces of process equipment?

Important planning note: This follows design, construction, commissioning, and super clean / as built certification.

  • Is your project being constructed as a part of a new “greenfield” project, or will the cleanroom be retrofitted into an existing structure?
  • Based on the answer to above question, what are the permitting requirements, certificate of occupancy requirements, and time barriers from the local officials?
  • What is the size and weight of the equipment that needs to run inside the cleanroom?
  • How will the equipment get to its final place?

Important planning note: Consider the size of the loading dock, hallways, elevator cab and door openings, doorways, etc.; plan an egress path up front.

Planning Tools

Successful projects start with planning and documenting requirements upfront. AdvanceTEC has proven tools available for clients to help in documenting requirements. To request the tools below, please click here to contact AdvanceTEC.

  • Utility Matrix for Nanotechnology & Microelectronics Cleanrooms: form for detailing equipment to be deployed and basic facilities requirements for that equipment
  • Chemical Usage Summary: form for documenting basic expectations for chemical usage and storage

Predecessors to Cleanroom Construction

Prior to initiating cleanroom construction, it is important to keep the following requirements in mind:

  • Your new building or existing building must be “dried in” and weather tight protected from the outside elements.
  • The concrete slab of your building where the cleanroom is to be located must pass the moisture content test for the flooring system to be installed to the manufactures stated specifications.
  • A vapor barrier building product and sealing techniques have been implemented to protect the cleanroom area from temperature, relative humidity and air exfiltration swings.
  • The dates where permanent utilities servicing the cleanroom will be commissioned and made available to the cleanroom have been identified.
  • Make up air to provide pressurization and conditioning (temperature / RH control) is in place.
  • Chilled water and steam if required for cleanroom HVAC systems has been provided.
  • Permanent stable and clean electrical power has been provided.
  • Building life safety; sprinklers, fire alarm, BMS (controls) are in place.

Helpful Tips

Below are important points to keep in mind when planning and executing your cleanroom project.

  • A cleanroom is a living, breathing, functioning system that must operate to its design parameters 24 hours per day, 365 days per year – regardless of the weather outside or what is taking place in other areas of your building, plant, or campus. To achieve this, the more accurate the information you provide, the better your facility will perform.
  • A cleanroom project requires active participation by you. An informed and engaged client who reviews information, activity participates in the process, and makes decisions in a timely fashion is critical to smooth and effective project execution and ultimately lower cost.
  • You get what you pay for. Breaking up a project between ten different contractors and materials suppliers may sound like a good idea, until you try to execute the project. A turn-key design build approach with a trusted firm like AdvanceTEC has been proven to be the fastest and lowest cost approach for executing a successful cleanroom project.  


Turn-key cleanroom design/build construction, and process tool installation & integration

AdvanceTEC Corporate Headquarters
11300 Business Center Drive
Richmond, Virginia 23236
Toll free: 1-877-560-8881
Tel: 804-378-1550 • Fax: 804-378-4055
Email: Support@AdvanceTECLLC.com